Regulating the Adaptive Immune Response to Blood-Stage Malaria: Role of...
Although a clearer understanding of the underlying mechanisms involved in protection and immunopathology during blood-stage malaria has emerged, the mechanisms involved in regulating the adaptive...
View ArticleTLR2 Mediates Immunity to Experimental Cysticercosis
Information concerning TLR-mediated antigen recognition and regulation of immune responses during helminth infections is scarce. TLR2 is a key molecule required for innate immunity and is involved in...
View ArticleParatransgenic Control of Vector Borne Diseases
Conventional methodologies to control vector borne diseases with chemical pesticides are often associated with environmental toxicity, adverse effects on human health and the emergence of insect...
View ArticleMucosal Delivery of ACNPV Baculovirus Driving Expression of the Gal-Lectin...
Mucosal vaccination against amoebiasis using the Gal-lectin of E. histolytica has been proposed as one of the leading strategies for controlling this human disease. However, most mucosal adjuvants...
View ArticleGastrointestinal Infection with Mexican TcI Trypanosoma cruzi strains:...
Mexican Ninoa and Queretaro (Qro) TcI strains of Trypanosoma cruzi have shown different degrees of virulence, and the two strains produce heterogeneous immune responses in the hearts of infected mice....
View ArticleSignal Transducers and Activators of Transcription (STAT) Family Members in...
Helminth parasites are a diverse group of multicellular organisms. Despite their heterogeneity, helminths share many common characteristics, such as the modulation of the immune system of their hosts...
View ArticleRole of Co-stimulation in Leishmaniasis
Leishmania are obligate intracellular parasites that cause a wide spectrum of diseases ranging from cutaneous, mucocutaneous and the visceral kind. Persistence or resolution of leishmaniasis is...
View ArticleCestode Antigens Induce a Tolerogenic-Like Phenotype and Inhibit LPS...
Pathogens have developed strategies to modify Dendritic Cells (DCs) phenotypes and impair their functions in order to create a safer environment for their survival. DCs responses to helminths and...
View ArticleNitric Oxide is Involved in the Upregulation of IFN-γ and IL-10 mRNA...
Nitric oxide (NO) is involved in the clearance of several types of bacteria, viruses and parasites. Although the roles of NO and CD8+ T cells in the immune response to malaria have been extensively...
View ArticleMechanisms Underlying the Induction of Regulatory T cells and Its Relevance...
To fulfill its function, the immune system must detect and interpret a wide variety of signals and adjust the magnitude, duration, and specific traits of each response during the complex host-parasite...
View ArticleSevere Malarial Anemia: Innate Immunity and Pathogenesis
Greater than 80% of malaria-related mortality occurs in sub-Saharan Africa due to infections with Plasmodium falciparum. The majority of P. falciparum-related mortality occurs in immune-naïve infants...
View ArticleProgesterone Induces Mucosal Immunity in a Rodent Model of Human Taeniosis by...
More than one quarter of human world's population is exposed to intestinal helminth parasites. The Taenia solium tapeworm carrier is the main risk factor in the transmission of both human...
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